This study assessed the level of knowledge of occupational hazards and compliance to safety measures among laboratory professionals in federal college of veterinary medical l laboratory technology Vom. The population for this study comprised thirty questionnaire (30) laboratory workers. A structured questionnaire that was given to the staff of FCVMLT. 83.3% are married, 53.3% agreed that they were given the necessary workplace health and safety training when starting a job, changing jobs or using new techniques, (46.7%). The dominance of male respondents over their female counterparts is due to the fact that male respondents were more accessible and willing to give information as compared to the females, while 43.3% strongly agreed that there are biological and non-biological hazards that is being experienced by Laboratory workers in FCVMLT, (40%) strongly agreed that they have experiences on non-biological hazard, 36.7% agreed that they have experiences on nonbiological hazard, (33.3%) agreed that there are risk factors associated with exposure to biological and non-biological hazards among health workers in FCVMLT, (30%) strongly agreed that are complying with the safety laboratory precautions, 26.7% agreed that are complying with the safety laboratory precautions, (23.3%) disagreed about the non-biological hazard, 16.7% are undecided about non-biological hazard, 3.3% strongly disagreed that they are complying with the safety laboratory precautions, and lastly 0.0% strongly disagreed that they have experiences on non-biological hazard. However, it was recommended that all Laboratory staff in institutions and the Ministry of health at all level should work in synergy to design and implement safety training and retraining programmes for laboratory workers.