Crime Prevention Through Environmental Design (CPTED) has become an important strategy for reducing crime and fear of crime in urban contexts by enhancing natural surveillance, territorial reinforcement, access control, and maintenance. Research in South African cities such as Gauteng and informal settlements like Inanda shows that environmental design interventions can influence safety perceptions, although implementation challenges remain around community involvement and coordination with government bodies. International evidence suggests that community engaged CPTED activities are associated with significant reductions in violent and firearm crime, illustrating the importance of multi stakeholder collaboration. This study uses a systematic literature review methodology to identify key factors that support or hinder effective CPTED implementation in South African urban areas, offering insights for policymakers, urban planners, and community stakeholders. Findings indicate that community engagement, contextualization to local conditions, resource allocation, policy frameworks, and ethical use of technology are critical determinants of CPTED success. This study highlights that the effective implementation of CPTED in South African urban areas depends on a holistic integration of community engagement, social cohesion, resource allocation, policy support, and ethical use of technology. Both South African and international evidence demonstrate that CPTED strategies can significantly reduce crime and enhance perceptions of safety when interventions are contextually adapted and collaboratively implemented. The findings provide critical insights for policymakers, urban planners, and community stakeholders, offering a roadmap for designing safer, more inclusive, and sustainable urban environments. By addressing systemic, social, and environmental factors, CPTED can serve as a transformative tool in shaping resilient and secure cities across South Africa.